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Wireless Miniaturised GonioPEN for irido-corneal imaging

Glaucoma is an irreversible condition where a build-up of pressure inside the eye causes damage to the optic nerve, leading to permanent vision loss. It will affect more than 76 million people by 2020 with the majority being in Asia. Early detection of glaucoma is critical in order to enable appropriate monitoring and treatment, which minimises the risk of irreversible vision loss.

Normally, fluid within the eye (called the aqueous humour) drains out through a mesh-like channel at the front of the eye. In angle closure glaucoma, the iris bulges forward to narrow or block the drainage angle. This results in a build-up of pressure, which damages the optic nerve. Of the different types of glaucoma, primary angle closure glaucoma (PACG) is more prevalent in Asia.

A team led by Associate Professor Shamira Perera from the Singapore National Eye Centre, has developed the GonioPEN. This is able to capture an image of the front portion of the eye, where the aqueous humour drains. Such a medical device is important for glaucoma categorization, diagnosis and monitoring.

The team has developed a prototype, which has demonstrated diagnostic capabilities similar to the current gold standard – gonioscopy. The team aims to develop this prototype into an inexpensive medical device that can provide a low cost, high performance solution for iridocorneal angle imaging. The team is currently working to refine their miniaturised prototype into a wireless handheld probe with integrated software that can automatically diagnose angle closure. The imaging probe will have a basic camera with LEDs and power source to image the angle of the eye with minimal contact at limbus. A smartphone may be used to view the images and control the probe.

Principal Investigator: Assoc Prof. Shamira Perera

Institution: Singapore National Eye Centre

NHIC Ref: NHIC-I2D-1912244



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