Seizure detection is a critical component of electroencephalography (EEG) interpretation. Non-convulsive seizures are especially common in the intensive care unit (ICU) setting, and timely seizure detection allows for early intervention…

Acute hydrocephalus, characterized by excessive cerebrospinal fluid (CSF) in the brain, is a common problem associated with stroke and head injury. Excessive CSF has to be constantly drained through an…

This project will demonstrate a home-based robotics-aided telerehabilitation solution for Singapore’s disabled and elderly population. With population aging in Singapore, demand for rehabilitation is expected to rise exponentially. For people…

Pain management during dental procedures is a cornerstone for successful everyday practice. Current dental practice delivers local anaesthesia using the traditional syringe and needle injection method. However, the appearance of…

Secretions from the cervix and vagina are routinely collected for laboratory testing. The current method requires a clinician to use a speculum and a separate cotton swab at the end…

The Zika virus (ZIKV) is an emerging infectious agent with severe socio-economic impact due to its potential detrimental effects on congenital malformation. However, accurate ZIKV diagnosis is complicated due to…

Post-procedural bleeding is commonly encountered in any acute-care hospital. However, when bleeding occurs and it is not discovered in time, it can potentially lead to serious long term consequences or…

Glaucoma is estimated to affect over 100 million people in the world by year 2040, half of which will reside in Asia. In Singapore, the prevalence of glaucoma is reported…

More than half of patients affected by the most common blinding diseases in the world (glaucoma, diabetic retinopathy) are not detected in time. The reason is that at their initial…

Neuraxial ultrasonography has become popular in last decade in epidural space identification. It has been shown a safe and effective technique, with increasing use as an auxiliary to physical examination,…

Bronchial asthma (BA) is one of the most common chronic illnesses in children with a prevalence of more than 14% globally. Evidence shows that the prevalence of asthma in children…

To unblock patient diseased heart vessels, cardiologists often place a stent prosthesis in the diseased artery to reopen and restore flow in the vessel. Current metal-based stents remain in the…

The technology is a method of determining the risk of cardiovascular disease (CVD) in patients with Type 2 Diabetes Mellitus (T2DM) as indicated by endothelial dysfunction. This is measured by…

Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling side effect of chemotherapy and occurs in up to 90% of patients. There is no specific treatment to prevent or reverse the severe…

Cricoid pressure refers to the finger pressure applied over the cricoid cartilage on the neck during intubation to prevent gastric aspiration into lungs in high-risk patients. Current “feel-based” gold standard…

Flap transfers are used to surgically reconstruct a patient’s body after trauma or cancerous tissue removal, using his/her own skin and muscle. However, post-surgical complications like vessel thrombosis and ischemia…

Patients presenting with chest pain may have a high risk of acute Major Adverse Cardiac Events (MACE), which could subsequently lead to death. This team has developed a device which…

Total laryngectomy involves the removal of a patient’s voice box and results in the loss of voicing capability. To restore the ability to speak, a voice prosthesis must be be…

Glaucoma is an irreversible eye disease and a leading cause of blindness worldwide. A major risk factor is increased intraocular pressure (IOP). When first-line treatments fail, glaucoma filtration surgery (GFS)…

No fewer than 230 million major surgeries are performed annually in the world which result in moderate to severe post-surgical pain. Intravenous patient-controlled analgesia with opioids is administered in more…

Muscle, our largest tissue mass, has evolved to assume a major homeostatic role over whole body maintenance and repair. As muscle uses physical activity to gauge its growth, inactivity causes…

Ultrasound (US) allows precise disease characterisation in rheumatoid arthritis. Presently, the most widely used synotivitis scoring system is semi-quantitative and involves a manual two-step process of image acquisition and interpretation,…

Diabetic retinopathy (DR) poses a large economic burden on the healthcare system with nearly 1 in 10 diabetes patients developing vision-threatening DR. Early detection, accurate evaluation and timely treatments are…

Appropriate lighting in the surgical theatres is crucial to the outcome of any surgery. While operating theatres are equipped with overhead lights, surgeons still struggle to gain proper visibility when…

Medication adherence in tuberculosis treatment is critical for patient’s cure, infection control and to minimize development of drug resistance. The current system of Directly Observed Therapy (DOT) involves daily clinic…

Mandible defects may result from trauma, inflammatory diseases or upon tumour resection. The gold standard for mandible reconstruction remains to be the microvascular free flap harvested from fibula bone. Despite…

Bedridden patients have increased risk of developing blood clots in their deep veins due to prolonged immobility, leading to deep vein thrombosis (DVT). In severe cases, blood clots in deep…

Age-related macular degeneration (AMD) and diabetic retinopathy (DR) are the leading causes of blindness in the elderly worldwide. Current treatments, while effective, are not ideal in terms of delivery nor…

Obesity and diabetes is a growing problem around the world. WHO estimates that in 2015, >13% of the population or >600million were obese. About 200million or ~30% of this obese…

Myopia is a global health burden, with projections predicting that one-third of the world’s population will have myopia by 2020. In Singapore alone, more than 50% of 9 year olds…

Diagnosis and management of neurological disorders relies on visual review of electroencephalogram (EEG) data by specialized physicians. As the duration of EEG recordings ranges from 30 minutes to several weeks,…

Good oral and dental hygiene can help to prevent tooth decay, gum disease and bad breath. A healthy mouth can help to ward off other medical disorders. For example, poor…

Visual impairment (VI) is an important public health issue. VI, which includes blindness, affects hundreds of millions globally, and has a substantial burden on the individual’s quality of life, as…

Wireless Miniaturised GonioPEN for irido-corneal imaging Glaucoma is an irreversible condition where a build-up of pressure inside the eye causes damage to the optic nerve, leading to permanent vision loss.…

Multiparametric MRI for the optimization of disease management in patients with concurrent NAFLD-CHB Due to the rising obesity epidemic, prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing. In parallel,…

A Novel 3D-Printed Patient-Specific Immediate Dental Implant Dental implants provide a reliable, safe and effective solution for a wide range of dental complications and diseases. This makes them an increasingly…