contact us

targetGroup_clinicianInnovators
targetGroup_ResearchAdministrator
targetGroup_IndustryPartner
targetGroup_Investor

Ultrasound (US) allows precise disease characterisation in rheumatoid arthritis. Presently, the most widely used synotivitis scoring system is semi-quantitative and involves a manual two-step process of image acquisition and interpretation, which can be subject to intra- and inter-rater variability among operators. The team will develop a fully automated ultrasound system to detect and quantify the thickened joint capsule (synovial hypertrophy) and the degree of active inflammation, seen as Power Doppler synovium vascularity. This will make the assessment process seamless, as well as eliminate the problem of rater reliability and such a technology will serve as an index for follow up examinations and therapy management.

Project Deliverables

A fully automated system to receive ultrasound joint images and provide an objective quantitative inflammation score and report through i) automatic detection and segmentation of the synovium (measuring its size), and ii) automatic detection and segmentation of the Power Doppler signal within the synovium area, and utilizing that information to quantify joint inflammation.


Principal Investigator: Dr TAN York Kiat

Institution: Singapore General Hospital

NHIC Ref: NHIC-I2D-1506048

 

 

See all MEDTECH projects >

Automated Bio-Imaging Platform for Rheumatoid Arthritis

Ultrasound (US) allows precise disease characterisation in rheumatoid arthritis. Presently, the m...

NEUROBROWSER™ — AN AUTOMATED EEG INTERPRETATION SYSTEM

Diagnosis and management of neurological disorders relies on visual review of electroencephalogra...

A Force Sensor to Deliver Optimal Cricoid Pressure for Airway Protection

Cricoid pressure refers to the finger pressure applied over the cricoid cartilage on the neck dur...

Assay for Early Detection of Flares in Patients with Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE) is an autoimmune condition which affects multiple organ system...

Towards a Novel Drug Therapy for Treatment-Resistant Depression: Adjunct 5-HTP Slow-Release

Depression is the leading cause of disability worldwide, and is a major contributor to the global...

Natriuretic peptide analogues for heart failure patients

Natriuretic peptide analogues with vasodilatory or renal activities for personalized care of hear...

OUR PARTNERS

Clinical Partners


nhg logonuhs logosinghealth

 

Academic Partners


lkc medicalnus faculty of dentistrynus sphnus somduke nus

 

Supporting Partners


bms ipodxdipinmrcSCRIseriSMARTEnterpriseSGCatalystSingaporeBioDesign